Allergic contact dermatitis caused by phenylethyl resorcinol [4-(1-phenylethyl)-1,3-benzenediol], a skin-lightening agent in cosmetics.

نویسندگان

  • Michi Gohara
  • Akiko Yagami
  • Kayoko Suzuki
  • Yusuke Morita
  • Akiyo Sano
  • Yohei Iwata
  • Takashi Hashimoto
  • Kayoko Matsunaga
چکیده

Allergic contact dermatitis caused by phenylethyl resorcinol [4-(1-phenylethyl)-1,3-benzenediol], a skin-lightening agent in cosmetics Michi Gohara1,2, Akiko Yagami1, Kayoko Suzuki3, Yusuke Morita1, Akiyo Sano1, Yohei Iwata1, Takashi Hashimoto2 and Kayoko Matsunaga1 1Department of Dermatology, Fujita Health University School of Medicine, Aichi, 470-1192, Japan, 2Department of Dermatology, Kurume University School of Medicine, Fukuoka, 830-0011, Japan, and 3Department of Dermatology, Kariya Toyota General Hospital, Aichi, 448-8505, Japan

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Allergic contact dermatitis caused by phenylethyl resorcinol, a skin-lightening agent contained in a sunscreen.

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Occupational contact dermatitis caused by 1,3-benzenedimethanamine, N-(2-phenylethyl) derivatives in hardeners for epoxy paints and coatings.

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Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications

Ethosome formulations containing phenylethyl resorcinol (PR) were developed. The formulation was produced from 0.5% w/v PR, 0.5% w/v cholesterol from lanolin, 3% w/v L-α-phosphatidylcholine from soybean, 30% v/v absolute ethanol, and water up to 100% v/v. It was characterized by a vesicular size of 389 nm, low polydispersity index of 0.266, zeta potential of -34.19 ± 0.44 mV, high PR entrapment...

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عنوان ژورنال:
  • Contact dermatitis

دوره 69 5  شماره 

صفحات  -

تاریخ انتشار 2013